About Indonal
Indonal
Composition:
Each capsule contains: Indole-3-carbinol, 150 mg (33.3%= RDD, i.e. recommended daily dose).
Excipient:
maize starch, 150 mg.
The product odor is characteristic for cruciferous plants and does not mean that the product quality has deteriorated.
Description:
Indole-3-carbinol is a substance, which is obtained by an efficient extraction from cruciferous plants, such as cabbage, broccoli, brassica (turnip), cole, cauliflower in the process of production of INDONAL dietary supplement.
The results of the scientific research to date demonstrate that one of the active components possibly supporting the positive reaction of human organism in response to certain tumors is the indole-3-carbinol.
Indole-3-carbinol is effective at several levels of cellular metabolism. Indole-3-carbinol has a positive effect on the estrogen metabolism by shifting the balance between the estrogen metabolites towards 2α- hydroxyestrone. This metabolic pathway does not lead to development of pathological changes and to the cancer of female sex organs dependent on estrogen. Indole-3-carbinol helps to suppress the growth of pre-cancer and cancer cells by blocking the growth factors and affecting the expression of genes p21, p27 and p53 with tumor suppressing activity. Indole-3-carbinol suppresses the activity of antigens E6 and E7, which are specific for HPV infections. By inhibition of these antigens indole-3-carbinol helps to change the HPV-altered cells to normal phenotype cells and supports the programmed death of cancer and HPV-altered cells.
INDONAL is intended for oral application, to be taken 5-10 minutes before food, with sufficient quantity of liquids.
Adults:
For prevention 2 capsules should be taken per day, over 1 – 2 months.
In presence of a disorder and female sex organ soft tissue cancer, infection by HPV in the anal and genital area, 2 capsules should be used per day over 3 months (3 capsules per day over 3 months are recommended for women over 70 kg)
For prostate and testicular tumors, polyps, cancer of colon, stomach and larynx, 2 capsules should be used per day over 3 months (3 capsules per day over 3 months are recommended for men over 70 kg)
Children:
Children over 3 years of age and body weight over 25 kg, the dosage recommendation is 6-7 mg per kg of body weight.
The recommended dosage must not be exceeded.
Repetition of the INDONAL treatment cycle is dependent on the results of the follow-up GYN examination. A 2-month pause is recommended before repeating the treatment cycle. Consult your specialist if you want to repeat the treatment cycle.
INDONAL may be used during radiotherapy. It can be used before and after chemotherapy, when using together with chemotherapy, reduced effect of INDONAL has been demonstrated.
INDONAL dietary supplement may be used together with hormonal contraception. It is suitable for diabetic patients.
Contraindications
Use of the INDONAL dietary supplement is highly contraindicated in pregnancy and during breast feeding!
It is not recommended to children younger below 3 years of age.
Use of the INDONAL dietary supplement is contraindicated in case of hypersensitivity to any of the components of the product.
INDONAL is not recommended in combination with medications reducing the secretion of gastric juices (antacids, H2 blockers, proton pump inhibitors (PPI)).
INDONAL is not effective in patients with mutation of cytochrome P450. In these patients indole-3-carbinol is not capable of affecting the transformation of estrogen to 2α- hydroxyestrone.
No adverse effects have been described when using the recommended daily dosage. In case of overdose, i.e. when more than 800 mg – corresponding to the maximum recommended daily dose - of the INDONAL dietary supplement is used, balance disruption, tremor, nausea and indigestion have been observed.
In some cases the product may cause flatulence, bloating, which resolves within several days.
It is important to observe the dosage schedule since irregular use and interruptions lead to the reduced effects of the INDONAL dietary supplement.
6x10 capsules
Minimum shelf life is indicated on outer packaging.
Stop using the product immediately if adverse effects occur!
Keep in dry and dark place at 10-25 °C.
Keep out of reach of children.
INDONAL is not a medical drug nor is it a substitute of varied and balanced diet.
INDONAL must not be used as a replacement for prescription drugs.
Regular checkups by gynecologist may prevent serious disorders; the use of the INDONAL dietary supplement is not a substitute for such checkups.
Consult your gynecologist before using the INDONAL dietary supplement.
Each capsule contains: Indole-3-carbinol, 150 mg (33.3%= RDD, i.e. recommended daily dose).
Excipient:
maize starch, 150 mg.
The product odor is characteristic for cruciferous plants and does not mean that the product quality has deteriorated.
Description:
Indole-3-carbinol is a substance, which is obtained by an efficient extraction from cruciferous plants, such as cabbage, broccoli, brassica (turnip), cole, cauliflower in the process of production of INDONAL dietary supplement.
The results of the scientific research to date demonstrate that one of the active components possibly supporting the positive reaction of human organism in response to certain tumors is the indole-3-carbinol.
Indole-3-carbinol is effective at several levels of cellular metabolism. Indole-3-carbinol has a positive effect on the estrogen metabolism by shifting the balance between the estrogen metabolites towards 2α- hydroxyestrone. This metabolic pathway does not lead to development of pathological changes and to the cancer of female sex organs dependent on estrogen. Indole-3-carbinol helps to suppress the growth of pre-cancer and cancer cells by blocking the growth factors and affecting the expression of genes p21, p27 and p53 with tumor suppressing activity. Indole-3-carbinol suppresses the activity of antigens E6 and E7, which are specific for HPV infections. By inhibition of these antigens indole-3-carbinol helps to change the HPV-altered cells to normal phenotype cells and supports the programmed death of cancer and HPV-altered cells.
Use:
INDONAL is a dietary supplement used to stimulate the positive reaction of human organism to the following tumor disorders and other diseases. It is suitable for individuals with health concerns or with confirmed diagnosis of- Cervical dysplasia (histological finding CIN I-III) and cervical cancer
- Infection by human papillomavirus HPV
- Genital warts and disorders affecting the anal and genital area (itching, keratosis, condylomatosis)
- Mastopathy (nodular and cystic changes in breasts)
- Breast cancer
- Uterine myomatosis
- Ovarian cysts
- Hormonal dysbalance in women
- Prostate and testicular cancer, polyps and cancer of colon and stomach, laryngeal mucosa tumors
INDONAL is intended for oral application, to be taken 5-10 minutes before food, with sufficient quantity of liquids.
Adults:
For prevention 2 capsules should be taken per day, over 1 – 2 months.
In presence of a disorder and female sex organ soft tissue cancer, infection by HPV in the anal and genital area, 2 capsules should be used per day over 3 months (3 capsules per day over 3 months are recommended for women over 70 kg)
For prostate and testicular tumors, polyps, cancer of colon, stomach and larynx, 2 capsules should be used per day over 3 months (3 capsules per day over 3 months are recommended for men over 70 kg)
Children:
Children over 3 years of age and body weight over 25 kg, the dosage recommendation is 6-7 mg per kg of body weight.
The recommended dosage must not be exceeded.
Repetition of the INDONAL treatment cycle is dependent on the results of the follow-up GYN examination. A 2-month pause is recommended before repeating the treatment cycle. Consult your specialist if you want to repeat the treatment cycle.
INDONAL may be used during radiotherapy. It can be used before and after chemotherapy, when using together with chemotherapy, reduced effect of INDONAL has been demonstrated.
INDONAL dietary supplement may be used together with hormonal contraception. It is suitable for diabetic patients.
Contraindications
Use of the INDONAL dietary supplement is highly contraindicated in pregnancy and during breast feeding!
It is not recommended to children younger below 3 years of age.
Use of the INDONAL dietary supplement is contraindicated in case of hypersensitivity to any of the components of the product.
Warning:
INDONAL is not recommended in combination with medications reducing the secretion of gastric juices (antacids, H2 blockers, proton pump inhibitors (PPI)).INDONAL is not effective in patients with mutation of cytochrome P450. In these patients indole-3-carbinol is not capable of affecting the transformation of estrogen to 2α- hydroxyestrone.
No adverse effects have been described when using the recommended daily dosage. In case of overdose, i.e. when more than 800 mg – corresponding to the maximum recommended daily dose - of the INDONAL dietary supplement is used, balance disruption, tremor, nausea and indigestion have been observed.
In some cases the product may cause flatulence, bloating, which resolves within several days.
It is important to observe the dosage schedule since irregular use and interruptions lead to the reduced effects of the INDONAL dietary supplement.
Packaging:
3x10 capsules6x10 capsules
Minimum shelf life is indicated on outer packaging.
Stop using the product immediately if adverse effects occur!
Keep in dry and dark place at 10-25 °C.
Keep out of reach of children.
INDONAL is not a medical drug nor is it a substitute of varied and balanced diet.
INDONAL must not be used as a replacement for prescription drugs.
Regular checkups by gynecologist may prevent serious disorders; the use of the INDONAL dietary supplement is not a substitute for such checkups.
Consult your gynecologist before using the INDONAL dietary supplement.
